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个人简介
Dr. Vaughan’s research is focused on defining and understanding the relevant cell types and molecular mechanisms by which the mammalian lung
is able to regenerate after severe injury. He is especially interested in elucidating the means by which epithelial progenitors contribute to repaired airway and alveolar units after various lung insults (influenza, ARDS, fibrosis). His studies suggest that physiological lung function is in fact dictated by progenitor cell fate choices after injury. Dr. Vaughan and his group have developed a novel orthotopic cell transplantation assay which allows for the direct assessment of engraftment, proliferation, and differentiation potential of these stem cells. Further, he is actively investigating the roles of the Notch, Wnt, and BMP pathways in regulating the differentiation potential and fate of expanded progenitor cells post-injury. His office and laboratory are located on the 3rd floor, office 370E Old Vet.
is able to regenerate after severe injury. He is especially interested in elucidating the means by which epithelial progenitors contribute to repaired airway and alveolar units after various lung insults (influenza, ARDS, fibrosis). His studies suggest that physiological lung function is in fact dictated by progenitor cell fate choices after injury. Dr. Vaughan and his group have developed a novel orthotopic cell transplantation assay which allows for the direct assessment of engraftment, proliferation, and differentiation potential of these stem cells. Further, he is actively investigating the roles of the Notch, Wnt, and BMP pathways in regulating the differentiation potential and fate of expanded progenitor cells post-injury. His office and laboratory are located on the 3rd floor, office 370E Old Vet.
研究兴趣
论文共 151 篇作者统计合作学者相似作者
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Paolo Panza, Till Lautenschläger, Gan Zhao, Mario Looso, Ondine Cleaver,Elisabeth Naschberger,Michael Stürzl,Andrew Vaughan,Didier Stainier
Molecular pathology and functional genomics (2024)
NATURE MATERIALS (2024)
Gan Zhao,Lulu Xue,Aaron I. Weiner,Ningqiang Gong,Stephanie Adams-Tzivelekidis,Joanna Wong,Maria E. Gentile,Ana N. Nottingham,Maria C. Basil,Susan M. Lin,Terren K. Niethamer,Joshua M. Diamond,Christian A. Bermudez,Edward Cantu,Xuexiang Han, Yaqi Cao,Mohamad-Gabriel Alameh,Drew Weissman,Edward E. Morrisey,Michael J. Mitchell,Andrew E. Vaughan
SCIENCE TRANSLATIONAL MEDICINEno. 732 (2024)
Biomaterials (2024): 122545-122545
Luis R Rodriguez,Konstantinos-Dionysios Alysandratos,Jeremy Katzen,Aditi Murthy,Willy Roque Barboza,Yaniv Tomer,Rebeca Acin-Perez,Anton Petcherski,Kasey Minakin,Paige Carson,Swati Iyer,Katrina Chavez, Charlotte H Cooper,Apoorva Babu,Aaron I Weiner,Andrew E Vaughan,Zoltan Arany,Orian S Shirihai, Darrell N Kotton,Michael F Beers
bioRxiv the preprint server for biology (2024)
biorxiv(2024)
ImmunoHorizonsno. 7 (2024): 478-491
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作者统计
#Papers: 151
#Citation: 3922
H-Index: 34
G-Index: 60
Sociability: 7
Diversity: 3
Activity: 84
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