Research Synopsis Professor Shapiro led the clinical team with the "Edmonton Protocol" islet transplant success, and was lead author on the 2000 NEJM study. He was PI on an international trial that replicated the Edmonton success, published in NEJM 2006. He has been the recipient of multiple awards, including the Hunterian Medal from the Royal College of Surgeons of England, the Gold Medal in Surgery from the Governor General of Canada, Physician of the Century, and was recently named one of Nature Biotechnology's most remarkable and influential personalities. He was elected Fellow of the Royal Society of Canada in 2012, and was recently appointed as the Department of Surgery's first Canada Research Council's Chair in Transplantation Surgery and Regenerative Medicine.