基本信息
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Career Trajectory
Bio
1970 : Faculty of Biology, Eötvös Loránd University, Budapest 1983: Candidate of Sciences ( Ph.D). 1990: Doctor of Science (DSc) Hungarian Academy of Sciences 。 2001: Corresponding member of the Hungarian Academy of Sciences。 2007: Ordinary member of the Hungarian Academy of Sciences。
since 2012 University Professor, Semmelweis University, Department of Genetics, Cell- and Immunobiology。 1994-2012 Professor and Chairman, Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary。 1975-1994 Co-chair for Department of Immunology, Head of Department, of Molecular Biology, National Institute of Rheumatology and Physiotherapy, Budapest , Hungary。 1970-1975 Researcher and assistant professor, Eötvös Loránd University, Budapest, Hungary。
Honours and Awards
Semmelweis Award from the Senate of Semmelweis University, 2008
Szechenyi Award from President of Hungarian Republic, 2006
Geoffrey B. West Award (European Histamine Research Society, 2006
Neumann Award for Bioinformatics, 2006
Kesztyüs Lorand award and medal for Hungarian Immunology 2005
„Scientist of the Year” in Hungary 2001
Arany János Foundation Award, 1998
Széchenyi professorial fellowship, 1997
Markusovszky award: 1996
Award of Hungarian Academy of Sciences 1995
Research areas:
1994 - The role of histamine in immune response, tumor growth. Phenotype analysis of histamine-free transgenic mice
1989 - 1994 Inflammatory cytokines, IL-6- the role of histamine in immune response, tumor growth, phenotype studies of histamine-free mice
1984 - 1988 Complement genetics, histamine
1975 - 1984 Immune complexes, beta-2 mikroglobulin
1970 - 1975 Neurochemistry, neuroimmunology
Selected publications
Yang XD, Ai W, Asfaha S, Bhagat G, Friedman RA, Jin G, Park H, Shykind B, Diacovo TG, Falus A, Wang TC. Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b(+)Ly6G(+) immature myeloid cells. Nature Med. 2011; 17:87-95.
György B, Módos K, Pállinger E, Pálóczi K, Pásztói M, Misják P, Deli MA, Sipos A, Szalai A, Voszka I, Polgár A, Tóth K, Csete M, Nagy G, Gay S, Falus A, Kittel A, Buzás EI. Detection and isolation of cell-derived microparticles are compromised by protein complexes due to shared biophysical parameters. Blood 2011; 117:e39-48.
Pos Z, Selleri S, Spivey T, Wang J, Liu H, Worschech A, Sabatino M, Monaco A, Leitman S, Falus A, Wang E, Alter H, and Marincola F Genomic scale analysis of racial impact on response to IFN alpha. Proc Natl Acad Sci U S A. 2010; 107:803-808.
Szabó TG, Palotai R, Antal P, Tokatly I, Tóthfalusi L, Lund O, Nagy G, Falus A, Buzás EI. Critical role of glycosylation in deterdetermining the length and structure of T cell epitopes. Immunome Res. 2009; 24; 5:4.
Pos Z, Wiener Z, Pocza P, Racz M, Toth S, Darvas Z, Molnar V, Hegyesi H, Falus A. Histamine suppresses fibulin-5 and insulin-like growth factor-II receptor expression in melanoma. Cancer Res. 2008; 68:1997-2005.
Molnar V, Tamasi V, Bakos B, Wiener Z, Falus A. Changes in miRNA expression in solid tumors: An miRNA profiling in melanomas. Semin Cancer Biol. 2008; 18:111-122.
Szalai C, Ungvári I, Pelyhe L, Tölgyesi G, Falus A. Asthma from a pharmacogenomic point of view. Br J Pharmacol. 2008; 153:1602-1614
Koncz A, Pasztoi M, Mazan M, Fazakas F, Buzas E, Falus A, Nagy G. Nitric oxide mediates T cell cytokine production and signal transduction in histidine decarboxylase knockout mice. J Immunol. 2007; 179:6613-6619.
Jelinek I, Laszlo V, Buzas E, Pallinger E, Hangya B, Horvath Z, Falus A. Increased antigen presentation and Th1 polarization in genetically histamine-free mice. Int Immunol. 2007;19:51-58.
Falus A, Hegyesi H, Lázár-Molnár E, Pós Z, László V, Darvas Zs. Paracrine and autocrine interactions in melanoma; histamine is a relevant player in local regulation. Trends in Immunology 2001;22:648-652.
Research Interests
Papers共 604 篇Author StatisticsCo-AuthorSimilar Experts
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HELIYONno. 5 (2024)
crossref(2023)
BIOLOGIA FUTURAno. 1-2 (2023): 91-99
openalex(2023)
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Author Statistics
#Papers: 606
#Citation: 17924
H-Index: 57
G-Index: 112
Sociability: 7
Diversity: 4
Activity: 3
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