I study the mechanisms underlying gynaecological disorders such as endometriosis, endometrial cancer and ovarian cancer. Major focus areas are: estrogen and progesterone signalling; mechanism of action of estrogen and progesterone receptors; local metabolism of steroid hormones and mechanisms of intracrinology. Methods and approaches: - clinical materials and biobanking - in vitro 2D and 3D models (spheroids, organoids) - in vivo models of estrogen-dependent gynaecologic diseases