I am a Professor of Medicine in the Department of Medicine and a member of the University of Maryland Greenebaum Comprehensive Cancer Center. I also have appointments in the Department of Pathology and Department of Molecular Biology and Biochemistry, University of Maryland School of Medicine. I have more than 25 years of experience as an academic medical oncologist. My clinical focus is in genitourinary cancers. I have conducted approximately 50 clinical trials, including investigator-initiated, cooperative group and sponsored clinical trials. I also have an active research laboratory that has been funded by various federal agencies for over 20 years. My research is in cell signaling in cancer cells and in drug resistance mechanisms, particularly in prostate cancer, with the long-term goal of identifying strategies to overcome resistance pathways and improve the efficacy of multi-targeted treatments in advanced prostate cancer. Another area of active, ongoing work is related to population-based studies using national registry datasets to better understand patient demographics, treatment patterns and potential disparities in treatment outcomes in cancer. I have served on the prostate cancer Merit Review Study Section for the Department of Veterans Affairs and the Scientific Review Panel for the National Institutes of Health. I am section editor for Current Opinion in Oncology, Genitourinary Cancers. As Co-Leader of the Hormone Responsive Cancers Program within the UMGCCC, I am involved in enhancing intra-programmatic and inter-programmatic translational and clinical collaborations.