Andrea De Maria

Present work aims at elucidating: - optimal clincal management protocols in cancer patients coinfected with chronic viruses and treated with immunomodulating biologicals (incl. TNF.inhibitors, Checkpoint inhibitors etc) - optimal management protocols for the prevention, identification and treatment of breast implant infection in breast cancer patients after breast reconstruction. - charcterizing the role of innate cell development (NK cells, ILC) from their precursors during chronic inflammation (infection, autoimmunity, cancer) - identifying innate or adaptive mechanisms underlying herpesvirus (CMV, HSV, VZV, HHV-8) exit from latency and their replication in patients with virus reactivation. - innate-adaptive crosstalk in the control of lentivirus (HIV-1, HTLV-1, HTLV-2) reservoir