Wanyi Hu - Department of Medicinal Chemistry, College of Pharmacy, University of Florida, 1333 Center Drive, Gainesville, FL, 32610, United States

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论文共 23 篇作者统计合作学者相似作者

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Targeted Degradation of Specific TEAD Paralogs by Small Molecule Degraders

Hui Chen,Artem Gridnev, Netanya Schlamowitz,Wanyi Hu, Kuntala Dey,Guangrong Zheng,Jyoti R. Misra

Heliyonpp.e37829-e37829, (2024)

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Development and Crystal Structures of a Potent Second-Generation Dual Degrader of BCL-2 and BCL-xL

Digant Nayak,Dongwen Lv,Yaxia Yuan,Peiyi Zhang,Wanyi Hu,Anindita Nayak,Eliza A. Ruben,Zongyang Lv,Patrick Sung,Robert Hromas,Guangrong Zheng,Daohong Zhou,Shaun K. Olsen

NATURE COMMUNICATIONSno. 1 (2024)

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Abstract 1209 Structural And Biochemical Studies Of Proteolysis-Targeting Chimera (PROTAC) Against Oncogenic Anti-Apoptotic Proteins, BCL-xl And Bcl-2

Digant Nayak, Dongwen Lyu,Wanyi Hu,Guangrong Zheng, Daohong Zhao,Shaun Olsen

Journal of Biological Chemistryno. 3 (2024)

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Design, Synthesis, and Evaluation of BCL-2 Targeting PROTACs

Alesa Bricelj,Yuen Lam Dora Ng,Martina Gobec,Robert Kuchta,Wanyi Hu, Spela Javornik, Miha Rozic,Michael Guetschow,Guangrong Zheng,Jan Kroenke,Christian Steinebach,Izidor Sosic

CHEMISTRY-A EUROPEAN JOURNALno. 45 (2024)

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A liver-tropic BCL-xL PROTAC effectively clears senescent hepatocytes and prevents NASH- driven HCC in mice

Yang Yang,Natacha Jn-Simon,Wanyi Hu,Peiyi Zhang,Guangrong Zheng,Liya Pi,Yonghan He,Daohong Zhou

Cancer Researchno. 2 (2023)

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Piperlongumine Conjugates Induce Targeted Protein Degradation

Jing Pei,Yufeng Xiao,Xingui Liu,Wanyi Hu,Amin Sobh,Yaxia Yuan,Shuo Zhou,Nan Hua,Samuel G. Mackintosh,Xuan Zhang,Kari B. Basso,Manasi Kamat,Qingping Yang,Jonathan D. Licht,Guangrong Zheng,Daohong Zhou,Dongwen Lv

Cell chemical biologyno. 2 (2023): 203-213.e17

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High-resolution genetic mapping and identification of candidate genes for the wheat stem rust resistance gene Sr8155B1

Jian Wang,Hongyu Li,Tao Shen, Shikai Lyu,Shams ur Rehman,Hongna Li,Guiping Wang,Binyang Xu,Qing Wang,Wanyi Hu, Kairong Li,Shengsheng Bai,Jian Ma,Haitao Yu,Matthew N. Rouse,Shisheng Chen

CROP JOURNALno. 6 (2023): 1852-1861

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Single-cell transcriptomic analysis of CLL cells at ibrutinib plus venetoclax relapse and targeting using BCL-2/BCL-xL PROTACs PZ18753b and WH25244

Daisy Diaz Rohena,Arnau Peris Cuesta,Bailey Slawin,Janani Ravikrishnan,Chaomei Liu,Charmelle Williams,Wanyi Hu,Peiyi Zhang,Phillip Thompson,William Wierda,Nitin Jain, Sachet Ashok Shukla,Guangrong Zheng,Daohong Zhou,Jennifer Woyach,Deepa Sampath

LEUKEMIA & LYMPHOMA (2023): S190-S191

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Accelerating Inhibitor Discovery for Deubiquitinating Enzymes

Wai Cheung Chan,Xiaoxi Liu,Robert S. Magin, Nicholas M. Girardi,Scott B. Ficarro,Wanyi Hu,Maria I. Tarazona Guzman, Cara A. Starnbach,Alejandra Felix,Guillaume Adelmant,Anthony C. Varca,Bin Hu,Ariana S. Bratt, Ethan DaSilva,Nathan J. Schauer, Isabella Jaen Maisonet,Emma K. Dolen, Anthony X. Ayala,Jarrod A. Marto,Sara J. Buhrlage

Nature Communicationsno. 1 (2023)

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Enriched Signalling Pathways in Venetoclax-Relapsed Chronic Lymphocytic Leukemia (CLL) Cells and Targeting Using a Protac-Based Bcl-2/Bcl-Xl Degrader

Daisy Diaz Rohena,Arnau Peris Cuesta,Bailey Slawin,Janani Ravikrishnan,Chaomei Liu,Charmelle Williams,Wanyi Hu,Peiyi Zhang,Philip Thompson,William G. Wierda,Nitin Jain,Sachet Shukla,Guangrong Zheng,Daohong Zhou,Jennifer A. Woyach,Deepa Sampath

Bloodno. Supplement 1 (2023): 4195-4195

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