I am a statistician with broad interest of application and development of statistical methods for ophthalmology and vision science. I use tools from hierarchical modelling, mixed effect models and multivariate models to address problems of disease prediction and classification using big data: imaging data, clinical data and longitudinally collected data. I am particularly interested in developments of statistical methods in the following three areas: 1) feature selection and statistical classification of retinal disease stages using imaging data, 2) multivariate modelling and classification for longitudinally collected observational clinical data; and 3) information measures for evaluation of surrogate and predictive biomarkers.