Genetic factors of pathogens as well as those of the hosts decisively influence the phenotype of a disease and the immune response. Therefore, a particular focus of our work is the genetic characterisation of pathogens and human genetic factors.The group also lead Vietnamese-German Center for Medical Research (www.vgcare.org). Distinct projects are ongoing The PAN ASEAN Coalition for Epidemic and Outbreak Preparedness (PACE-UP: www.paceup.org), a Center for global health and pandemic prevention.