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个人简介
My research focus has been on improving treatments for older patients who have acute and chronic leukemia. My colleagues and I pioneered the use of reduced-intensity conditioning regimens for older or more debilitated patients with blood cancers. Before this discovery, older patients with these diseases were rarely considered candidates for stem cell transplantation procedures using donor cells because of the toxic effects of high-dose chemotherapy. The development of these less intense and less toxic regimens has allowed us to perform transplants for older patients in a safe and effective manner and has changed the standard of care throughout the world. I plan to continue this research in the context of the pioneering T cell depletion techniques developed at Memorial Sloan Kettering. This new approach has dramatically reduced the risk of graft-versus-host disease, a serious complication of donor stem cell transplantation. Disease recurrence after transplantation remains an important cause of treatment failure, and I am a proponent of post-transplant maintenance therapies using a variety of targeted therapies, which we are continuing to explore at Memorial Sloan Kettering
研究兴趣
论文共 1548 篇作者统计合作学者相似作者
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TRANSPLANTATION AND CELLULAR THERAPYno. 1 (2024): 81-92
Issam S. Hamadeh,Tala Shekarkhand,Colin Rueda,Ross S. Firestone,Alice X. Wang,Neha Korde,Malin L. Hultcrantz,Alexander M. Lesokhin,Sham Mailankody,Hani Hassoun,Urvi A. Shah,Kylee Maclachlan,Sridevi Rajeeve,Dhwani Patel,Gunjan L. Shah,Michael Scordo,Oscar B. Lahoud,David J. Chung,Heather J. Landau,Sergio Giralt,Saad Z. Usmani,Carlyn R. Tan
British journal of haematologyno. 4 (2024): 1429-1438
Rachel Lorenc,Roni Shouval,Jessica R. Flynn,Sean M. Devlin,Amethyst Saldia,Alejandro Luna De Abia,Magdalena Corona De Lapuerta,Ana Alarcon Tomas, Giulio Cassanello,Lori A. Leslie,Kai Rejeski,Richard J. Lin,Michael Scordo,Gunjan L. Shah,M. Lia Palomba,Gilles Salles,Jae Park,Sergio A. Giralt,Miguel-Angel Perales,Andrew Ip
Transplantation and Cellular Therapy (2024)
Transplantation and Cellular Therapyno. 2 (2024): S348
Madhavi Lakkaraja,Audrey Mauguen,Devin McAvoy,Kinga Hosszu, Katina H Singh, Esther H Vidal, Dr. Valerie Stewart, Gabrielle Schmidt,John E Levine,Miguel-Angel Perales,Sergio A. Giralt, K. Scott Baker,Jaap-Jan Boelens
Transplantation and Cellular Therapyno. 2 (2024): S439
Marcelo C. Pasquini,Robert Soiffer,Brent Logan,Manmeet Kaur,Steven M. Devine,Nancy Geller,Sergio A. Giralt,Helen E. Heslop,Mary M. Horowitz,Mark R. Litzow,Adam Mendizabal,Lori S Muffly,Eneida Nemecek,Lynn C. O'Donnell,Johannes Schetelig,Leyla Shune,Scott R. Solomon,Sumithira Vasu, Dr. Vincent T. Ho,Miguel-Angel Perales
Transplantation and Cellular Therapyno. 2 (2024): S48-S49
Transplantation and Cellular Therapyno. 2 (2024): S145
Karthik Nath,Tala Shekarkhand,David Nemirovsky,Andriy Derkach,Bruno Almeida Costa,Noriko Nishimura,Tasmin Farzana,Colin Rueda,David J. Chung,Heather J. Landau,Oscar B. Lahoud,Michael Scordo,Gunjan L. Shah,Hani Hassoun,Kylee Maclachlan,Neha Korde,Urvi A. Shah,Carlyn Rose Tan,Malin Hultcrantz,Sergio A. Giralt,Saad Z. Usmani, Zainab Shahid,Sham Mailankody,Alexander M. Lesokhin
Blood Cancer Journalno. 1 (2024): 1-8
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作者统计
#Papers: 1547
#Citation: 46207
H-Index: 106
G-Index: 186
Sociability: 9
Diversity: 0
Activity: 10
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