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Cross was the first to identify the VSG family and characterize VSG genes, which led to the discoveries of messenger RNA trans-splicing and a mechanism for protein anchoring to the cell membrane, called glycophosphatidylinositol (GPI) anchoring, which has since been found to be used in a wide range of organisms, including in some important human proteins. Trypanosomes use GPI anchoring to a greater extent than almost any other organism, and there are some unique features of GPI anchoring in these parasites that are still not well understood.
From 1970 to 1977 he worked in the Medical Research Council Biochemical Parasitology Unit in Cambridge. He then joined the Wellcome Research Laboratories of the Wellcome Foundation in England, where he headed the department of immunochemistry, which later became the department of molecular biology. Cross came to Rockefeller in 1982. In 1984 Cross was a recipient of the Paul Ehrlich and Ludwig Darmstaedter Prize, awarded in Germany, and he received the Chalmers Memorial Medal of the Royal Society of Tropical Medicine and Hygiene in 1983. He is a fellow of The Royal Society.
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#Papers: 195
#Citation: 17186
H-Index: 73
G-Index: 127
Sociability: 6
Diversity: 3
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