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个人简介
Kaufman's current research still heavily involves the HOX gene. He is currently interested in proteome changes in the head of the aging Drosophila. In his personal statement for the National Academy of Sciences he states that "The goal of my laboratory is to contribute to an understanding of the genetic regulation development of higher organisms. The homeotic (Hox) genes of Drosophila melanogaster have been our principal focus. Homeotic lesions cause one portion of the animal to be transformed into an identity normally found elsewhere. The role of the Hox genes is best viewed as a set of developmental switches for decisions of segmental fate. The encoded homeodomain has shown that this switch activity is carried out through the transcriptional regulation of target genes." He has expanded his research from Drosophila to include several other insects and members of other subphylums under the phylum Arthopoda, such as Crustacea, Chelicerata and Myriapoda. He uses the technique of RNA-mediated gene inhibition (RNAi) to study the evolution of the HOX gene.
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Julie Agapite,Laurent-Philippe Albou,Suzi Aleksander,Joanna Argasinska,Valerio Arnaboldi,Helen Attrill,Susan M Bello,Judith A Blake,Olin Blodgett,Yvonne M Bradford,Carol J Bult,Scott Cain,Brian R Calvi,Seth Carbon,Juancarlos Chan,Wen J Chen,J Michael Cherry,Jaehyoung Cho,Karen R Christie,Madeline A Crosby,Jeff De Pons,Mary E Dolan,Gilberto dos Santos,Barbara Dunn,Nathan Dunn,Anne Eagle,Dustin Ebert,Stacia R Engel,David Fashena,Ken Frazer,Sibyl Gao,Felix Gondwe,Josh Goodman,L Sian Gramates,Christian A Grove,Todd Harris,Marie-Claire Harrison,Douglas G Howe,Kevin L Howe,Sagar Jha,James A Kadin,Thomas C Kaufman,Patrick Kalita,Kalpana Karra,Ranjana Kishore,Stan Laulederkind,Raymond Lee,Kevin A MacPherson,Steven J Marygold,Beverley Matthews,Gillian Millburn,Stuart Miyasato,Sierra Moxon, Hans-Michael Mueller,Christopher Mungall,Anushya Muruganujan,Tremayne Mushayahama,Robert S Nash,Patrick Ng,Michael Paulini,Norbert Perrimon,Christian Pich,Daniela Raciti,Joel E Richardson,Matthew Russell, Susan Russo Gelbart,Leyla Ruzicka,Kevin Schaper,Mary Shimoyama,Matt Simison,Cynthia Smith,David R Shaw, Ajay Shrivatsav,Marek Skrzypek,Jennifer R Smith,Paul W Sternberg,Christopher J Tabone,Paul D Thomas,Jyothi Thota,Sabrina Toro,Monika Tomczuk,Marek Tutaj,Monika Tutaj,Jose-Maria Urbano,Kimberly Van Auken,Ceri E Van Slyke,Shur-Jen Wang,Shuai Weng,Monte Westerfield,Gary Williams,Edith D Wong,Adam Wright,Karen Yook
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#Papers: 84
#Citation: 6980
H-Index: 39
G-Index: 68
Sociability: 6
Diversity: 3
Activity: 6
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