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Research Interests
Point-of-Care Tests for emerging pathogens. We are developing novel molecular Point of Care (PoC) methods required for detection of emerging pathogens (e.g., Flavi virus (Zika), Coronavirus (SARS-CoV-2) and human papilloma virus (HPV)) that are low-cost and do not require extensive equipment. Simple sample collection and purification is followed by isothermal amplification (e.g., rolling circle amplification (RCA), recombinase polymerase amplification (RPA)), after which the amplified product is captured and colorimetrically detected by lateral flow assay.
Positioning Biosensors. We have constructed Whole Cell Biosensors that allow to monitor bioluminescent gene expression in bacterial biofilms. When these bacteria are grown on agar plates at various densities, they express bioluminescence not only in a density- but also in a position-dependent manner (quorum sensing (QS) and positional sensing (PS), respectively). The use of bioluminescence in QS and PS promises to reveal important regulatory circuits and communication systems relevant for bacterial normal physiology, pathogenicity and virulence.
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论文共 181 篇作者统计合作学者相似作者
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Journal of Water Process Engineering (2024): 105789
Mengrui Li,Stephanie Vanegas,Mia R. Gonzalgo, Joseph A. Lacret,Wensi Tao,Sapna Deo,Sylvia Daunert,Jean-Marc Zingg
Aspects of Molecular Medicine (2024): 100039
Journal of Biological Chemistryno. 3 (2023): 103118-103118
Jean-Marc Zingg,Yu-Ping Yang, Spencer Seely,Pratibha Joshi,Md Harun Or Roshid, Fabiola Iribarren Latasa,Gregory O'Connor,Jennifer Alfaro,Eduardo Riquelme,Sebastian Bernales,Emre Dikici,Sapna Deo,Sylvia Daunert
Aspects of Molecular Medicine (2023): 100002-100002
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#Papers: 181
#Citation: 8263
H-Index: 49
G-Index: 87
Sociability: 6
Diversity: 3
Activity: 12
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