Kidney diseases are often asymptomatic or present nonspecifically and are frequently diagnosed by chance as part of a laboratory check up. In newly diagnosed renal failure, the physician should determine the dynamics (acute versus chronic) and identify the cause of the renal dysf...
Objective: GH excess in acromegaly leads to lower fat mass and insulin resistance; both reverse following pituitary surgery. Soluble delta like-1 homolog (sDlk1) inhibits adipocyte differentiation and may mediate the antiadipogenic effects of GH. It is released into the circulati...
Swiss Medical Forum ‒ Schweizerisches Medizin-Forum (2022)
Der 74-jährige Patient stellte sich im September 2019 aufgrund einer Präsynkope und seit vier Tagen bestehender grippaler Symptome vor. Er berichtete über Fieber, Kopf- und Gliederschmerzen sowie Appetitlosigkeit mit vereinzeltem Erbrechen. Den fünftägigen Urlaub am Gardasee mit ...
Chronic necrotizing pulmonary aspergillosis (CNPA) is characterized by fungal invasion of the lung parenchyma causing local destruction [1–5]. It usually occurs in elderly patients with underlying lung disease and in association with diabetes mellitus, low-dose corticosteroids or...
Background: Serum cystatin C (CysC) is a marker for kidney function, possibly superior to serum creatinine (Cr). Cr is increased and CysC decreased in primary hypothyroidism; these changes are reversed upon thyroxine (T4) replacement therapy. This (pilot) study was performed to s...
Background: Chronic obstructive pulmonary disease (COPD) exacerbations are associated with disease progression, worsening health status, more hospitalizations and COPD-related mortality. During stable COPD, the identification of patients at high risk for exacerbations has a high ...
Abstract Background: The release of hormones from the adrenal gland is vital in acute and chronic illnesses such as chronic obstructive pulmonary disease (COPD) involving recurrent exacerbations. Using a metabolomic approach, we aim to investigate associations of different adrena...
Swiss Medical Forum ‒ Schweizerisches Medizin-Forum (2016)
Neuroendokrine Tumoren der Lunge sind eine heterogene Gruppe von Tumoren, die vom low-grade-Karzinoid bis zum high-grade-kleinzelligen Bronchialkarzinom reicht. Die vorliegende Übersichtsarbeit stellt die Epidemiologie, Diagnostik, Behandlung und Prognose der einzelnen Tumorenti...
We report the case of a young man with a history of attention deficit/hyperactivity disorder and mild cognitive impairment who presented with chronic fatigue, anorexia and progressive darkening of the skin. On laboratory testing, severely depressed concentrations of morning corti...
Addisonian crisis is the life-threatening acute manifestation of adrenal insufficiency due to absolute or relative glucocorticoid deficiency. Adrenal haemorrhage is a rare condition of unknown incidence with the risk of adrenal insufficiency and death, not uncommonly first being ...
Summary The relapse of follicular lymphoma (FL) within 24 months (POD24) of chemoimmunotherapy has been associated with poor survival. We analyzed a pooled dataset of three randomized trials including FL patients with advanced disease, conducted by the Swiss Group for Clinical Ca...
OBJECTIVE:The purpose of this study was to investigate whether the prenatal diagnosis of a 'lean' umbilical cord in otherwise normal fetuses identifies fetuses at risk of being small for gestational age (SGA) at birth and of having distress in labor. The umbilical cord was define...
Introduction: Despite advances in critical care medicine, adjunctive approaches in sepsis therapy have failed to prove their efficacy. Notwithstanding promising results using hemoadsorption (CytoSorb), questions remain concerning timing and dosing. We created a dynamic scoring sy...
Zusammenfassung. Die Bildgebung bei Wirbelsäulenerkrankungen ist in den letzten Jahren einem starken Wandel unterlegen. Immer bessere MRI-Techniken führen zu immer genaueren Aussagen, wobei aber unverändert die enge Korrelation zwischen Klinik und Bildgebung für die korrekte Diag...