BJCP British journal of clinical pharmacology/British journal of clinical pharmacology (2017): 813-815
Opioid prescribing and its associated harm are at record levels globally. In the USA, a 4-fold increase in opioid prescriptions, deaths and treatment admissions was observed between 1999 and 2009, and has risen every year since 1. Tramadol, fentanyl and oxycodone are major culpri...