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Neoadjuvant PARPi or Chemotherapy in Ovarian Cancer Informs Targeting Effector Treg Cells for Homologous-Recombination-deficient Tumors

Yikai Luo,Yu Xia,Dan Liu,Xiong Li,Huayi Li,Jiahao Liu,Dongchen Zhou,Yu Dong,Xin Li,Yiyu Qian,Cheng Xu, Kangjia Tao,Guannan Li, Wen Pan, Qing Zhong, Xingzhe Liu,Sen Xu,Zhi Wang,Ronghua Liu,Wei Zhang, Wanying Shan, Tian Fang, Siyuan Wang, Zikun Peng, Ping Jin, Ning Jin, Shennan Shi, Yuxin Chen, Mengjie Wang, Xiaofei Jiao, Mengshi Luo, Wenjian Gong, Ya Wang, Yue Yao, Yi Zhao, Xinlin Huang, Xuwo Ji, Zhaoren He, Guangnian Zhao, Rong Liu, Mingfu Wu, Gang Chen, Li Hong, Ding Ma, Yong Fang, Han Liang, Qinglei Gao

CELL(2024)

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关键词
HGSOC,HRD,neoadjuvant therapy,PARP inhibitor,chemotherapy,tumor microenvironment,single-cell transcriptomics,tumor-reactive T cell,effector Treg,CCR8
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