Evaluating the between-day reliability and likelihood of change of a test battery incorporating vastus lateralis muscle thickness, ankle-brachial pressure index, maximal voluntary torque, and six-minute walk test in patients with claudication
VASCULAR(2024)
Abstract
Objective The study aims to evaluate the between-day reliability of a proposed test battery for patients with claudication that can be used for monitoring the effectiveness of exercise interventions and other therapeutic strategies tailored to this patient population.Methods Twenty-five men with claudication were recruited. The test battery consisted of the Vastus Lateralis muscle thickness (VL-MT), ankle-brachial pressure index (ABI), unilateral isometric knee extension maximal voluntary torque (MVT) and 6-minute walk test (6MWT). A single investigator conducted the tests for each patient on two separate testing sessions (T1 and T2) 5-7 days apart.Results Good to excellent reliability was observed for VL-MT (ICC = 0.95, 95% LOA = +/- 3.10 mm, SEM = 0.81 mm), ABI (ICC = 0.97, 95% LOA = +/- 0.10, SEM = 0.02), MVT (ICC = 0.97, 95% LOA = +/- 24.0 Nm, SEM = 6.31 Nm), 6MWT distance (ICC = 0.99, 95% LOA = +/- 39.6 m, SEM = 11.0 m), 6MWT time to claudication (ICC = 0.99, 95% LOA = +/- 30.8 s, SEM = 7.8 s), and 6MWT ratings of pain (ICC = 0.87, 95% LOA = +/- 2.4 CR-10+, SEM = 0.7 CR-10+ ). Analysis derived from reliability data indicates a change of 1.4 mm for VL-MT, 0.14 for ABI, 12 Nm for MVT, 25 m for 6MWT distance, 15 s for 6MWT time to claudication and 1 CR-10+ for 6MWT ratings of pain is required to be interpreted as the minimum 'likely' change (76% chance).Conclusions The test battery provides a reliable assessment of patients with claudication and can be widely used to evaluate the effects of exercise programmes and other therapeutic interventions. For the individual, changes in VL-MT, ABI, MVT, and 6MWT greater than the minimum likely change as a result of an exercise programme or an intervention are likely changes and less influenced by error associated with the test.
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Key words
Peripheral artery disease,Six-minute walk test,Ankle-brachial index,maximal voluntary torque,muscle thickness
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