New Secondary Metabolites from Marine-Derived Fungus Talaromyces Minnesotensis BTBU20220184
Marine drugs(2024)
摘要
Six new compounds, talamitones A and B (1 and 2), demethyltalamitone B (3), talamiisocoumaringlycosides A and B (4 and 5), and talaminaphtholglycoside (6), together with six known compounds (7–12), were isolated from the marine-derived fungus Talaromyces minnesotensis BTBU20220184. The new structures were characterized by using HRESIMS and NMR. This is the first report of isocoumaringlycoside derivatives from a fungus of the Talaromyces genus. Compounds 5, 6, and 9 showed synergistic antibacterial activity against Staphylococcus aureus.
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关键词
marine-derived fungus,Talaromyces minnesotensis,antibacterial,Staphylococcus aureus
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