Publication rates of registered strabismus trials from ClinicalTrials.gov

Leo Meller, Angel Bert Sambo,Nam Nguyen,Shira L. Robbins,David B. Granet

Journal of American Association for Pediatric Ophthalmology and Strabismus(2024)

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摘要
Presently, little is known regarding the characteristics and publication rates of registered strabismus trials from ClinicalTrials.gov. We queried registered strabismus trials that were completed prior to January 1, 2021, from ClinicalTrials.gov. Publication of trials in peer-reviewed journals was confirmed using PubMed.gov, ClinicalTrials.gov, and Google Scholar. Of the 117 trials found, only 69 (59%) were published with a publication delay of nearly 2.5 years. Interventional trials were associated with publication status compared with observational trials. The low publication rates and significant publication delay indicate potential bias in information dissemination of completed strabismus trials.
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