ICOS Agonist Vopratelimab Modulates Follicular Helper T Cells and Improves B Cell Function in Common Variable Immunodeficiency

Ali Sepahi,Hsi-En Ho, Prapti Vyas,Benjamin Umiker,Katalin Kis-Toth,Dmitri Wiederschain,Lin Radigan,Charlotte Cunningham-Rundles

CLINICAL IMMUNOLOGY（2024）

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关键词

Common variable immune deficiency,Inducible T cell co-stimulator (ICOS) activation,Follicular helper T cells,IL-10 and IL-21 secretion,IgG1 production,Follicular helper T cell modulation

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