Prognostic significance of systemic immune inflammatory index in NSCLC: a meta-analysis
LUNG CANCER MANAGEMENT(2024)
Abstract
Aim: The aim of this meta-analysis was to investigate the relationship between the baseline systemic immune inflammatory index (SII) and prognosis in patients with NSCLC. Materials & methods: The relation between pretreatment SII and overall survival, disease-free survival, cancer-specific survival, progression-free survival and recurrence-free survival in NSCLC patients was analyzed combined with hazard ratio and 95% CI. Results: The results showed that high SII was significantly correlated with overall survival and progression-free survival of NSCLC patients, but not with disease-free survival, cancer-specific survival and recurrence-free survival. Conclusion: The study suggests that a higher SII has association with worse prognosis in NSCLC patients.PROSPERO registration number: CRD42022336270.
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Key words
baseline,meta-analysis,NSCLC,prognosis,systemic immune inflammation index (SII)
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