2-(Sulfanylmethyl)indol-3-yl Acetic Acid Derivatives: Synthesis and in Silico Prediction of Anti-Inflammatory Activity

{2-[(2-Hydroxyethyl)sulfanylmethyl]indol-3-yl}acetic ester and hydrazide were synthesized for use in the directed synthesis of {2-[(2-hydroxyethyl)sulfanylmethyl]indol-3-yl}acetic acid–derived pyrazole. Predictive analysis and in silico calculations of the bioavailability, potential toxicity, and anti-inflammatory activity of the synthesized compounds were carried out by molecular docking assessment of their inhibitory activity against cyclooxygenases.