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Association of Euterpe oleracea, Bixa orellana, Myciaria dubia, and Astrocaryum aculeatum (the Terasen® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans

Journal of ageing and longevity(2023)

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摘要
Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.
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关键词
longevity,healthspan,lifespan,nutraceuticals
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