Relationships of BRAF V600E Gene Mutation With Some Immunohistochemical Markers and Recurrence Rate in Patients With Thyroid Carcinoma.

Tri Bui Dang Minh,Thuan Nghiem Duc,Van Phan Nguyen Thanh,Tuan Dinh Le,Minh Duc Tong,Trung Hoang Nguyen,Anh Le Tuan,Kien Xuan Nguyen,Tien Tran Viet,Thang Ba Ta,Son Tien Nguyen,Hai Anh Vu,Ba Van Nguyen,Dung Nguyen Thi Ngoc,Viet Tran Quoc,Thanh Bui Duc

Clinical Medicine Insights. Oncology（2023）

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摘要

A high prevalence of BRAF V600E gene mutation was found in thyroid carcinoma patients. The rates of positive HBME-1, COX-2, and Ki67 markers were significantly correlated to BRAF V600E gene mutation. Patients with BRAF V600E gene mutation showed a significantly higher relapse rate and earlier relapse time than those without the mutation.

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