Grevillosides R-S: Glucosides of 5-Alkylresorcinol Derivatives from Roots of Ardisia Crispa (thunb.) A. DC.
Natural product research(2023)
摘要
Grevillosides R-S (1-2), two new glucosides of 5-alkylresorcinol derivatives, were isolated from the roots of Ardisia crispa (Thunb.) A. DC. The structures of grevillosides R-S (1-2) were determined by 1D and 2D NMR, HR-MS, UV, IR experiments and by comparison of their spectroscopic and physical data with literature values. In this paper, grevillosides R-S (1-2) were tested for their radical-scavenging activity (DPPH and ABTS) and alpha-glucosidase inhibitory activity in vitro. Grevillosides R-S (1-2) exhibited weak DPPH radical-scavenging activity with IC50 values of 72.3 and 485.2 mu M, respectively. Grevillosides R-S (1-2) exhibited no inhibitory activity against alpha-glucosidase. [GRAPHICS] .
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关键词
Primulaceae,Ardisia crispa (Thunb.) A. DC,5-alkylresorcinol derivatives,antioxidant activity,alpha-glucosidase inhibitory activity
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