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[Acetaldehyde dehydrogenase 2 ameliorates lung endothelial barrier and balances mitochondrial dynamics in mice with acute lung injury].

L Wang, M Tian,R Li,Y Wu,S Wang, H Lü, Z Liu,Y Yu

Nan fang yi ke da xue xue bao = Journal of Southern Medical University（2023）

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Abstract
ALDH2 can ameliorate LPSinduced lung endothelial barrier damage in ALI mice by maintaining the balance of mitochondrial dynamics and inhibiting oxidative stress, and the mechanism may be related to the Nrf2/HO-1 pathway.
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Key words
ameliorates lung endothelial barrier,acetaldehyde,acute lung injury,mitochondrial dynamics
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