The influence of tissue pH and RNA integrity number on gene expression of human postmortem brain.

Kazusa Miyahara,Mizuki Hino,Zhiqian Yu,Chiaki Ono,Atsuko Nagaoka, Masataka Hatano,Risa Shishido,Hirooki Yabe,Hiroaki Tomita,Yasuto Kunii

Frontiers in psychiatry（2023）

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摘要

The current study elucidated the influence of pH and RIN on gene expression profiling and identified gene sets whose expressions were affected by tissue pH or RIN. These findings would be helpful in the control of confounders for future postmortem brain studies.

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schizophrenia, postmortem brain, microarray, pH, RNA integrity number

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