Resveratrol promotes gluconeogenesis by inhibiting SESN2-mTORC2-AKT pathway in calf hepatocytes.

This study indicated that resveratrol enhances the gluconeogenic capacity of calf hepatocytes by improving HO-induced oxidative stress and modulating the activity of the SESN2-mTORC2-AKT pathway, implying that resveratrol may be a promising target for ameliorating liver oxidative stress in transition cows.