Fe(OTf)(3)-Catalyzed Synthesis of Boronic Ester Containing N,O-Acetal Structure

A convenient approach acess to boronic ester containing N,O-acetal structure has been established through the Fe(OTf)(3)-catalyzed addition of N,O-acetal with organic boric acid. A series of N-O-acetal boronic ester compounds have been successfully prepared in 58%similar to 98% yields. Moreover, these compounds retain the property of boronic ester and can be used for coupling reaction.