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Comparison of multiple whole-genome andSpike-only sequencing protocols for estimating variant frequencies via wastewater-based epidemiology

Lucy A. Winder,Paul Parsons,Gavin Horsburgh,Kathryn Maher,Helen Hipperson,Claudia Wierzbicki,Aaron R. Jeffries,Mathew R. Brown,Aine Fairbrother-Browne,Hubert Denise,Mohammad S. Khalifa,Irene Bassano,Ronny van Aerle,Rachel Williams, Kata Farcas,Steve Paterson,Paul G. Blackwell,Terry Burke

medRxiv (Cold Spring Harbor Laboratory)（2022）

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Key words
variant frequencies,epidemiology,whole-genome,wastewater-based
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