Liraglutide Treatment is Associated with Progression of Coronary Artery Fibrous Plaque: a Prospective 1-Year Follow-Up Study in Asymptomatic Patients with Type 2 Diabetes.

The objective of this study was to assess the association between clinically indicated liraglutide treatment and coronary artery plaque progression during 1-year follow-up in asymptomatic diabetes. Patients were divided into a group receiving liraglutide (Lira+) and a group not receiving liraglutide (Lira-). Coronary computed tomography angiography (CCTA) was performed to assess total atheroma volume (TAV) and subtypes of plaque volumes (dense calcium, fibrous, fibrous-fatty, and necrotic core plaque) and the plaque progression during one year follow-up. Fifty-five patients (27