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Case report: Blepharospasm in peak-dose dyskinesia may benefit from amantadine in Parkinson's disease

FRONTIERS IN NEUROLOGY(2022)

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Abstract
IntroductionBlepharospasm is uncommon in Parkinson's disease, especially in the peak-dose dyskinesia period. Case presentationWe herein present the case of a patient with PD who developed blepharospasm in the peak-dose dyskinesia period. The symptom was improved by taking amantadine. ConclusionThe current report expands the phenomenology of peak-dose dykinesia in PD to include dystonic blepharospasm. This complication of levodopa therapy may respond to amantadine despite the dystonic appearance of movements.
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Key words
blepharospasm,Parkinson's disease,peak-dose dyskinesia,amantadine,dyskinesia
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