Vaccination with designed neopeptides induces intratumoral, cross-reactive CD4+ T cell responses in glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research（2022）
摘要
Turning tumor self-peptides into foreign antigens by introduction of designed mutations is a promising strategy to induce strong intratumoral CD4+ T cell responses in a cold tumor like glioblastoma.
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关键词
designed neopeptides induces intratumoral,glioblastoma,vaccination,cross-reactive,t-cell
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