Dietary xylitol supplement ameliorated AD related neuronal injury by regulating glucose metabolism relevant amino acids in mice.

Mengjia Jin,Xintong Ji,Xiaozheng Zhu,Yikai Shou,Zhiwei Ge,Huanhuan Wang

CNS & neurological disorders drug targets（2022）

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摘要

The current study suggests that xylitol may be a potential candidate for improving neuropsychiatric behavior in AD by regulating the levels of TCA cycle intermediates and related amino acids in glucose metabolism.

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关键词

Alzheimer's disease,Xylitol,anxiety-like symptoms,glucose metabolism,mitochondrial dysfunction,neuronal injury.

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