Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

Sylvanus Okogbenin,Cyril Erameh,Joseph Okoeguale,Osahogie Edeawe, Esele Ekuaze,Kelly Iraoyah, John Agho,Mirjam Groger,Benno Kreuels,Lisa Oestereich,Femi O. Babatunde,Peter Akhideno,Stephan Gunther,Michael Ramharter,Till Omansen

Emerging infectious diseases（2022）

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摘要

Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin.

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Lassa fever,Lassa virus,viruses,ribavirin,dexamethasone,viral hemorrhagic fever

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