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MSR18 The Effect of Weight Loss on Hypothalamus Structure and Function in Obese Individuals: A Systematic Literature Review and Meta-Analysis

D Gedda,RA Mekary,S Devi,N Yadav,S Chawla,J Doucette,LD Moura,LA Velloso

VALUE IN HEALTH（2022）

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Abstract
Obesity (body mass index (BMI) ≥ 30 kg/m2) is usually presented with structural and functional hypothalamic dysfunction. However, it is currently unclear whether weight loss can modify these hypothalamic changes. We, therefore, aimed to conduct a systematic review and meta-analysis to determine the effect of body mass reduction in obese individuals on hypothalamic structure and function.
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Key words
weight loss,hypothalamus structure,obese individuals,meta-analysis meta-analysis
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