Nontherapeutic Risk Factors of Different Grouped Stage IIIC Breast Cancer Patients' Mortality: A Study of the US Surveillance, Epidemiology, and End Results Database.
The breast journal(2022)
摘要
Objectives. Stage IIIC breast cancer, as a local advanced breast cancer, has a poor prognosis compared with that of early breast cancer. We further investigated the risk factors of mortality in stage IIIC primary breast cancer patients and their predictive value. Methods. We extracted data from the US Surveillance, Epidemiology, and End Results (SEER) database of female patients with stage IIIC primary breast cancer (n = 1673) from January 2011 to December 2015. Results. Hormone receptor negativity (P <= 0.001 and P = 0.001, respectively), aggressive molecular typing (P <= 0.001 and P <= 0.001, respectively), high T stage (P <= 0.001 and P = 0.001, respectively), a high number of positive lymph nodes (>= 14) (P = 0.005 and P = 0.001, respectively), and lymph node ratio (>= 0.8148) (P <= 0.001 and P <= 0.001, respectively) were associated with poor disease-specific survival. (e indicators of disease-specific survival included estrogen receptor status, progesterone receptor status, molecular typing, T stage, number of positive lymph nodes, and lymph node ratio (P <= 0.001, P <= 0.001, P <= 0.001, P <= 0.001, P = 0.002, and P <= 0.001, respectively). Conclusion. Hormone receptor negativity, aggressive molecular typing, high T stage, high number of positive lymph nodes, and lymph node ratio are poor prognostic factors patients with stage IIIC primary breast cancer. (e efficient indicators of disease-specific survival include estrogen receptor status, progesterone receptor status, molecular typing, T stage, number of positive lymph nodes, and lymph node ratio.
更多查看译文
关键词
Breast Cancer
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要