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Glioblastoma-instructed Microglia Transition to Heterogeneous Phenotypic States with Phagocytic and Dendritic Cell-Like Features in Patient Tumors and Patient-Derived Orthotopic Xenografts

Yahaya A. Yabo,Pilar M. Moreno-Sanchez,Yolanda Pires-Afonso,Tony Kaoma, Bakhtiyor Nosirov,Andrea Scafidi, Luca Ermini, Anuja Lipsa,Anaïs Oudin,Dimitrios Kyriakis,Kamil Grzyb,Suresh K. Poovathingal,Aurélie Poli,Arnaud Muller,Reka Toth,Barbara Klink,Guy Berchem,Christophe Berthold,Frank Hertel,Michel Mittelbronn,Dieter H. Heiland,Alexander Skupin,Petr V. Nazarov,Simone P. Niclou,Alessandro Michelucci,Anna Golebiewska

Genome Medicine（2024）

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关键词
Glioblastoma,Tumor microenvironment,Myeloid cells,Microglia,Patient-derived orthotopic xenografts,Single-cell RNA sequencing
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