Proteomic and Phosphoproteomic Landscapes of Acute Myeloid Leukemia.

Michael H. Kramer,Qiang Zhang,Robert Sprung,Ryan B. Day,Petra Erdmann-Gilmore, Yang Li,Ziheng Xu,Nichole M. Helton,Daniel R. George,Yiling Mi,Peter Westervelt,Jacqueline E. Payton,Sai M. Ramakrishnan,Christopher A. Miller,Daniel C. Link,John F. DiPersio,Matthew J. Walter,R. Reid Townsend,Timothy J. Ley

Blood（2022）

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摘要

Key Points A deep-scale proteomic and phosphoproteomic database of AML was produced and can be explored interactively (www.leylab.org/amlproteome). Posttranscriptionally regulated proteins were identified globally and associated with specific AML-initiating events.

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关键词

Phosphoproteomics,AML,Proteomics

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