FACILE AND EFFICIENT N-BOC DEPROTECTION OF AMIDE AND SULFONAMIDE UNDER MICROWAVE IRRADIATION IN WATER

A facile and efficient microwave-assisted N-Boc deprotection of amide and sulfonamide in water was developed. With environmentally friendly, operational-simplicity, good substrate scope and excellent product yields, this methodology is superior to the existing approach. Significantly, the target compound was obtained after filtration and dry.