人骨髓间充质干细胞成软骨分化过程中长链非编码RNA差异表达的研究
Chinese Journal of Experimental Surgery(2022)
Abstract
人骨髓间充质干细胞(human bone marrow mesenchymal stem cells,hBMSCs)是一种来源于中胚层的成体干细胞,可作为种子细胞定向诱导成软骨分化修复软骨损伤
[1]。本研究利用转录组测序技术,鉴定并分析骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMSCs)诱导成软骨分化前后长链非编码RNA(long non-coding RNA,lncRNA)表达谱的变化特征,探讨lncRNA在BMSCs成软骨分化调控中的作用机制。
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