Adrenocorticotropic Hormone Induced Status Dystonicus: Caution Advised

Dystonia is a movement disorder characterized by involuntary sustained or intermittent muscle contraction causing repetitive twisting movements and abnormal postures. The localization of dystonia is dysfunctional interactions of basal ganglia, cerebellum, thalamus, cerebral cortex and brainstem. Status dystonicus, or dystonic storm, is a life threatening emergency marked by development of increasingly frequent or continuous severe episodes of generalized dystonic spasms. The etiology of status dystonicus has not been clearly. We hereby present a case report of a child with WS who went on to develop status dystonicus following intramuscular ACTH injection.