Novel GPR87/SDC-1 Complex Modulates Lacritin Rescue of Homeostasis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology(2022)
Abstract
Lacritin appears to bind directly to the outer loop domains of GPR87 as part of a preformed SDC1-GPR87 complex - the latter linked in part by glycosaminoglycans and apparently by cytoplasmic SDC1 and GPR87 domains to regulate ocular surface health.
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