A case of angiolipoma of the upper lip

Angiolipoma is a benign tumor that shows a mixture of adipose tissue and hemangioma-like lesion histologically. It frequently occurs in the trunk and limbs, and it is very rare in the lip. We report a case of angiolipoma of the upper lip. The patient was a 28-year-old woman who was referred to our hospital because of a mass in the right upper lip. A painless elastic-soft tumor was found under the mucosa of the right upper lip. The skin and mucosa just above the swelling was normal. MRI showed an unclearly demarcated lesion measuring 13 × 11 × 5 mm in the right upper lip with a mixed pattern of high and low intensity on T1- and T2-weighted images. An incisional biopsy was performed under local anesthesia, and the histopathological diagnosis was angiolipoma. Based on this diagnosis, the tumor was resected under general anesthesia. Immunohistochemical examination revealed CD31, CD34, α-SMA and VEGF positive cells in the tumor. There has been no recurrence one year after surgery.