Functional lineage tracing to study the clonal evolution of therapy resistance
NATURE REVIEWS CANCER（2022）
摘要
In this Tools of the Trade article, Christian Umkehrer describes the development and use of CaTCH, which enables therapy-naive cancer cell clones to be isolated and compared to their resistant counterparts.
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关键词
Cancer therapeutic resistance,Genetic engineering,Next-generation sequencing,Biomedicine,general,Cancer Research
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