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Abstract 243: Caspase-1 Mediates Muscle Fiber Typing and Functionality in Response to Ischemia

Ricardo José Ferrari,Xiangdong Cui,Abish Pius,Amrita Sahu,Sunita Shinde,Fabrisia Ambrosio, Hong Liao,Melanie J. Scott,Ulka Sachdev

Arteriosclerosis, Thrombosis, and Vascular Biology（2019）

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Abstract
Introduction: We have shown that chloroquine (CQ), a lysosomal inhibitor, increases inflammatory cleaved caspase-1 in myocytes, and improves ischemic muscle histology in mice. This is relevant to m...
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muscle,fiber
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