Effects of Sleep Disorders and Fatigue on HIV Disease Progression in Older Children and Adolescents

M.E. Paul,P.Y. Brouwers,D.G. Glaze,J.M. Reuben,B. Lee,L.L. Harris,C.A. Kozinetz,M.W. Kline,H.L. Schwarzwald,S.B. Foster,C.D. Jackson,W.T. Shearer

The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology（2005）

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摘要

RATIONALE: Children with chronic illnesses have sleep disruption, daytime attention deficits, and impulsivity, and altered blood leukocyte subtypes, sleep-regulating hormones, and pro- and anti-inflammatory cytokines. Children with HIV infection exhibit similar sleep disorders and fatigue, but their effects upon HIV disease progression and immunity are unknown.

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