Yeni P-Alkilaminofenol Bileşiklerinin Sentezi Ve Antimikrobiyal Ve Antioksidan Aktivitelerinin Araştırılması

Alkylaminophenols are synthetic derivatives well known for their anticancer activity.In this work, we report the antimicrobial and antioxidant activity of such compounds.A series (4,5,6) of alkylaminophenol compounds were prepared with fairly good yields by Petasis reaction.Synthesized compounds were characterized by 1 H-NMR and 13 C-NMR.The obtained compounds were tested against Gram-positive and Gram-negative bacteria.The compound 4 showed antimicrobial activity at a concentration of 10 mg/mL, while the 6 compound showed activity on S. aureus.Phenolic compounds have attracted attention due to their proximal and antioxidant activities.Since alkylaminophenols have phenolic structure, their antioxidant activity has been investigated.Thus, drug-active substances with high antioxidant capacity against diabetes, heart disease, and cancer were synthesized.