Tu1245 - The Risk of Diarrhea and Colitis in Patients with Advanced Melanoma Undergoing Immune-Checkpoint Inhibitor Therapy
Gastroenterology(2018)
Abstract
steroids alone, however a significant proportion have disease that is refractory to steroids and require escalation of therapy.Some colitis cases are refractory to medical therapy and require colectomy.Severe cases of hepatitis may require ATG.Further prospective studies need to be conducted in the hospital setting to explore potential clinical, biochemical or histological predictors of steroid failure, to establish the relationship between these markers and the need for immunosuppressive therapy beyond steroids alone. Tu1244
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Key words
colitis,diarrhea,immune-checkpoint
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