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A suppression switch

Hanna Starobinets,Jayanta Debnath

Nature（2013）

Cited 10|Views2
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Abstract
The status of the protein p53 determines whether inhibiting the cellular autophagy pathway promotes or inhibits pancreatic cancer in mice. This finding serves as a cautionary tale for clinical trials of autophagy inhibitors. See Letter p.296
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Key words
Cancer,Cell biology,Drug discovery,Science,Humanities and Social Sciences,multidisciplinary
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